Saccharomyces cerevisiae essential genes with an Opi- phenotype.

TitleSaccharomyces cerevisiae essential genes with an Opi- phenotype.
Publication TypeJournal Article
Year of Publication2014
AuthorsSalas-Santiago B, Lopes JM
JournalG3 (Bethesda)
Volume4
Issue4
Pagination761-7
Date Published2014 Apr
ISSN2160-1836
KeywordsCluster Analysis, Genes, Essential, Histone Acetyltransferases, Inositol, Phenotype, Phospholipids, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Abstract

The overproduction and secretion of inositol (i.e., Opi(-)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.
DOI10.1534/g3.113.010140
Alternate JournalG3 (Bethesda)
PubMed ID24558266
PubMed Central IDPMC4059245
Grant ListR25GM086264 / GM / NIGMS NIH HHS / United States
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