Title | Unraveling the secrets of regulating mitochondrial DNA replication. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Klingbeil MM, Shapiro TA |
Journal | Mol Cell |
Volume | 35 |
Issue | 4 |
Pagination | 398-400 |
Date Published | 2009 Aug 28 |
ISSN | 1097-4164 |
Keywords | Animals, DNA Helicases, DNA Replication, DNA, Kinetoplast, DNA, Mitochondrial, DNA, Protozoan, Gene Expression Regulation, Mutation, Peptide Hydrolases, Protozoan Proteins, Time Factors, Trypanosoma brucei brucei |
Abstract | In this issue, Liu et al. (2009) report that maxicircle DNA copy number in trypanosomes is regulated by proteolysis of a helicase; the complex kinetoplast DNA system yields a clear view of how mitochondrial DNA replication can be regulated. |
DOI | 10.1016/j.molcel.2009.08.007 |
Alternate Journal | Mol. Cell |
PubMed ID | 19716784 |
Department of Microbiology